Effect of Snakehead Fish Nugget and Colored Fruit Juice on Immune Response (CD4, TLC, and Leukocytes) in People Living with HIV (PLWHIV)

Authors

  • Ginta Siahaan Politeknik Kesehatan Kemenkes Medan
  • Urbanus Sihotang Politeknik Kesehatan Kemenkes Medan, Jurusan Gizi
  • Jujuren Sitepu Politeknik Kesehatan Kemenkes Medan, Jurusan Kebidanan
  • Iceratnalela Siregar Politeknik Kesehatan Kemenkes Medan, Jurusan Teknologi Laboratorium Medis

DOI:

https://doi.org/10.21776/ub.ijhn.2021.008.02.4

Keywords:

Snakehead Fish, Colored Fruit, Immunity, HIV / AIDS

Abstract

Human Immunodeficiency Virus (HIV) is a virus attacking the body's defense system in people living with HIV (PLHIV), such as Cluster Of Differentiation 4 (CD4), Leukocytes, and Total Lymphocyte Count (TLC). People infected with HIV require adequate macro and micronutrients to improve their quality of life. The content of protein, albumin, zinc, and bioactive substances contained in food ingredients can increase the immune response. Snakehead fish nuggets are rich in Albumin and Zn, while colored fruit juice contains bioactive substances and is high in Vitamin C. This study aimed to determine the impact of snakehead fish nuggets and colored fruit juices on CD4, leukocytes, and TLC in PLHIV in Medan. This research was a Quasi Experiment with a pre and post-test design. The sample represented an entire population of 36 people from all residents of the Rehabilitation Center and was then given the treatment of snakehead fish nuggets and colored fruit juices for 22 days. The data analysis was performed using the T-dependent test after the data were normally distributed. The results showed a treatment impact on CD4, leukocytes, and TLC in PLHIV with a p-value <0.05. 

Author Biography

  • Ginta Siahaan, Politeknik Kesehatan Kemenkes Medan
    Dosen Politeknik Kesehatan Kemenkes Medan, Jurusan Gizi

References

Noviana, Nana. Catatan Kuliah Kesehatan Reproduksi dan HIV/AIDS. Jakarta : CV. Trans Info Media. 2018

Kemenkes RI. Profil Kesehatan Indonesia 2016. Jakarta UNAIDS. Global Report,

UNAIDS Report on The Global AIDS Epidemic. Geneva: WHO. 2017

Warouw, dkk. The effect Of Snack Head Fish Extract Supplements to the enhancenement of Nutritional Status, Levels of Albumin, Hb And Level of CD4 on Pregnant Woman with HIV/AIDS Who Acquiret Antriretroviral Therapy in Papua. IJSBAR. 2016; 30(4) p : 384-397

Fitri Handayani, Fatwa Sari. Faktor yang Mempengaruhi Kualitas Hidup Orang

dengan HIV/AIDS di Kota Kupang. Jurnal of Communy Medicine and Public Health. 2017; 33(11) p: 509-514.

Kasim Vivien Novarina, Sri Manovita Patede, Veni Hadju, Nurhaedar Jafar.

Suplementasi Ektrak Ikan Gabus Terhadap Status Gizi Dan Imunitas Pasien

Stroke. Jurnal Gizi Klinik Indonesia. 2017 ; 13(3) p : 91-98.

Bratawidjaja. Imunologi Dasar. Balai Penerbit FKUI. Jakarta: 2014. p : 186-189

Harikedua VT, Walalangi RGM, Sahelangi O. Suplementasi protein

ikan gabus sebagai alternative dalam penatalaksanaan diet pada pasien dengan

indikasi hypoalbuminemia di RSUP Prof. Dr. R.D. Kandou Manado. Gizi Indo. 2014. p : 228-236

Cindytia P, Sedarnawati Y, dan Mala N. Karasteristik Protein Ikan

Gabus Yang Berpotensi Sebagai Antihiperglikemik. Jurnal Pengolahan Hasil

Perikanan Indonesia. 2017; 20(3) p: 413-423.

Pettalolo S.R. Efek Suplementasi Ekstrak Ikan Gabus dan Vitamin C terhadap Kadar

Hemoglobin, Leukosit, Limfosit, Albumin, dan IMT Pada Pasien HIV/AIDS. Gizi

Indonesia. 2015; 38(1) p : 41-48.

Almatsier S, Penuntun Diet. Gramedia : Jakarta 2013. p : 205-214

Farid, MD. dkk. Nutritional Value And Medicinl Benefits of Peneaple. International Journal Of Nutrition And Food Scieces. 2015. p : 84-88

Notoatmodjo. Metodologi Penelitian Kesehatan, Jakarta: Rineka Cipta. 2016.

Kementrian RI. Statistik Kasus HIV/AIDS di Indonesia Dilapor s/d Juni 2016. Jakarta, Indonesia: Ditjen PP & PL KEMENKES RI. 2016.

Cahyani, dkk. Gambaran Perilaku Beresiko HIV pada Pengguna Napza suntik di Provinsi Jawa Tengah. Jurnal Promosi Kesehatan Indonesia. 2015; 10(1) p : 1-16

Hutapea, MD. dkk. Karakteristik Penderita HIV/AIDS di Klinik VCT Rumah Sakit Umum HKBP Balige. Jurnal Gizi, Kesehatan Reproduksi dan Epidemiologi. 2012. p :1-10

Mubarak, et al. Promosi Kesehatan Sebuah Pengantar Proses Belajar mangajar Dalam Pendidikan. Yogyakarta: Graha Ilmu. 2011.

Lovena A, dkk. Karateristik Pasien Sirosis Hepatitis di RSUP Dr. M.Djamil Padang. Jurnal Kesehatan Andalas. 2017 ; 6(1)

Amirruddin R, Yanti F. Tindakan Berisiko Tertular HIV-AIDS pada Anak Jalanan di Kota Makassar. Universitas Hasanuddin. 2012. p : 1-19

Kumar, A, et.al. Determinants of quality of life among people living with HIV/AIDS: a cross sectional study in central karnataka, India. International Journal of Medical Science and Public Health. 2013; 3(11) p : 54-57

Rahfiludin M, dkk. Pengaruh Suplementasi Seng Terhadap CD4 Pengidap Human Immunodeficiency Viruz. Kesehatan Masyarakat FKM UNDIP. Semarang. 2013; 5(1) p 31-39.

Wardhani P., Nurbaini. Pengaruh Pemberian Jus Nenas Dan Jus Pepaya Sebagai

Pendamping ARV Dalam Meningkatkan Kadar CD4. Jurnal Vokasi Kesehatan. 2016;

(1) p :78-83.

Puertollano, dkk. Dietary antioxidants: immunity and host defense. Curr Top Med Chem. 2011. p : 52–66.

Regina V, dkk. Hubungan Kadar Limfosit Total dengan Prognosis Penyakit pada Penderita Sirosis Hati di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas. 2013; 2(2) p : 98-100

Widjaja NA. Pengaruh Penyakit Infeksi Terhadap Kadar Albumin Anak Gizi Buruk. Sari Pediatri. 2012; 15(1) p : 46-50

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Published

2021-11-29

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How to Cite

1.
Effect of Snakehead Fish Nugget and Colored Fruit Juice on Immune Response (CD4, TLC, and Leukocytes) in People Living with HIV (PLWHIV). IJHN [Internet]. 2021 Nov. 29 [cited 2025 Mar. 17];8(2):129-38. Available from: https://ijhn.ub.ac.id/index.php/ijhn/article/view/484

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