Kadar High Sensitivity C-Reactive Protein Berkaitan dengan Lingkar Pinggang pada Lansia

Authors

  • Deny Yudi Fitranti Departemen Ilmu Gizi Fakultas kedokteran Universitas Diponegoro
  • Bunga Syifarahmi Departemen Ilmu Gizi Fakultas kedokteran Universitas Diponegoro
  • Martha Ardiaria Departemen Ilmu Gizi Fakultas kedokteran Universitas Diponegoro
  • Nurmasari Widyastuti Departemen Ilmu Gizi Fakultas kedokteran Universitas Diponegoro

DOI:

https://doi.org/10.21776/ub.ijhn.2021.008.01.3

Keywords:

Lingkar Pinggang, Rasio Lingkar Pinggang Panggul, hs-CRP, Lansia

Abstract

Proses penuaan mempengaruhi peningkatan distribusi lemak abdominal dengan indikator lingkar pinggang (LP) dan rasio lingkar pinggang panggul (RLPP). Penimbunan lemak abdominal menyebabkan disfungsi jaringan adiposa sehingga mempengaruhi biomarker proinflamasi yaitu kadar serum high-sensitivity C-reactive Protein (hs-CRP). Penelitian bertujuan untuk mengetahui hubungan LP dan RLPP dengan kadar hs-CRP lansia wanita. Rancangan penelitian cross sectional pada 53 subjek dipilih secara consecutive sampling. Antropometri yang diukur adalah LP dan RLPP. Pengukuran kadar serum hs-CRP dianalisis dengan metode enyme-linked immunosorbent assay (ELISA). Wawancara yang dilakukan yaitu data diri, asupan, aktivitas fisik, dan riwayat konsumsi obat. Data asupan diperoleh dengan metode food recall 3x24 jam. Aktivitas fisik diperoleh menggunakan International Physical Activity Questionnaire (IPAQ). Analisis data digunakan uji korelasi Spearman. Hasil penelitian menunjukkan bahwa persentase LP pada lansia wanita yang berisiko sebesar 90,6%, RLPP yang berisiko sebesar 98,1%, dan kadar hs-CRP tinggi sebesar 30,2%. Terdapat hubungan positif antara LP dengan kadar serum hs-CRP (r=0,417 ; p=0,002). Dalam penelitian ini RLPP, aktivitas fisik, asupan energi, karbohidrat, protein, lemak, serat, vitamin A, vitamin C, vitamin D,vitamin E, dan selenium tidak berkorelasi dengan kadar hs-CRP. Simpulan penelitian ini adalah LP berkorelasi positif dengan kadar serum hs-CRP, namun RLPP tidak berkorelasi dengan kadar serum hs-CRP

References

  • Kementrian Kesehatan RI. Analisis Lansia di Indonesia. Jakarta: Kemenkes RI;2017. 1-2.
  • Konda S, Ravi Kumar BP, Giri PA. Prevalence of Malnutrition and Its Determinants in an Elderly People in South India. Int J Community Med Public Heal. 2018;5(8):3570-6.
  • Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of Obesity Among Adults and Youth: United States, 2015–2016. NCHS Data Brief. 2017;288:1-8.
  • Badan Penelitian dan pengembangan kesehatan Kemenkes RI. Hasil utama Riskesdas 2018. Jakarta: Kemenkes RI; 2018.
  • Patidar O. Higher Prevalence Rate of CHD in “Apple Type of Obesity†Cases as Compared to “Pear Type Obesity†Cases. Indian J Clin Pract. 2013;23(12):791–4.
  • Ross R, Neeland IJ, Yamashita S, Shai I, Seidell J, Magni P, et al. Waist circumference as a vital signin clinical practice: A concensus statement from the IAS and ICCR working group on visceral obesity. Nature Reviews Endocrinology, 2020;16:177-189
  • WHO. Waist Circumference and Waist-Hip Ratio: Report of a WHO Expert Consultation. Geneva: WHO; 2008.
  • Waspadji S, Sukardji K. Pengkajian Status Gizi : Studi epidemiologi. Jakarta: Fakultas Kedokteran Universitas Indonesia; 2013.p.1-314
  • Paley CA, Johnson MI. Abdominal Obesity and Metabolic Syndrome: Exercise As Medicine? BMC Sports Sci Med Rehabil. 2018;10(1):1–8.
  • Lee H, Lee IS, Ghoue R. Obesity, inflammation and Diet. Pediatr gastroenterol hepatol Nutr. 2013; 16(3): 143-152.
  • Rojo-Martínez G, Soriguer F, Colomo N, Calle A, Goday A, Bordiú E, et al. Factors Determining High-Sensitivity C-Reactive Protein Values In The Spanish population. Diabetes Study. Eur J Clin Invest. 2013;43(1):1–10.
  • Blaha MJ, Rivera JJ, Budoff MJ, Blankstein R, Leary DHO, Cushman M, et al. Association Between Obesity, Hs-CRP > 2 mg/L, and Subclinical Atheroslerosis: Implications of JUPITER from the Multi-Ethnic Study of Atherosclerosis. Arter Thromb Vasc Biol. 2011;31(6):1430–8.
  • Li Y, Zhong X, Cheng G, Zhao C, Zhang L, Hong Y, et al. Hs-CRP and all cause, cardiovascular and cancer mortality risk: A-meta-analysis. Atherosclerosis. 2017;259:75-82.
  • Zain A, Al-Safi, Alex J. Obesity and menopause. Best Practice & Research Clinical Obstetrics & Gynaecology. 2015; 29(4): 548-553.
  • Buffa R, Floris GU, Putzu PF, Marini E. Body Composition Variations in Ageing. Coll Antropol. 2011;35(1):259–65.
  • Assuncao LGS, Eloi-Santos SM, Peixoto SV, Lima-Costa MF, Vidigal PG. High Sensitivity C-Reactive Protein Distribution in the Elderly: the Bambui Cohort Study, Brazil. Braz J Med Biol Kes. 2012;45(12):1284–6.
  • Sastroasmoro S, Sofyan I. Dasar-Dasar Metodologi Klinik. Jakarta: Bina Rupa Aksara. 2014. p.130-7.
  • Wahyuni N, Murbawani EA. Hubungan lingkar pinggang dan rasio lingkar pinggang panggul dengan kadar serum high sensitivity C-reactive protein (hsCRP) remaja obesitas. Journal of Nutrition College. 2017; 5(4): 388-392.
  • Suguna, Jayarajan MP. Association of Menopause with Inflammation-Sensitive Protein the C-Reactive Protein Among the Indian Women. J Evol Med Dent Sci. 2013;2(52):10144–53.
  • Bybee KA, Dew ML, Lawhorn SL, Stevens TL. Penyakit Kardiovaskuler pada Wanita: Buku Saku Klinis. Jakarta: Erlangga; 2014. 1-198
  • Wang Z, Wang X, Chen Z, Zhang L, Zhu M. Distribution of High-Sensitivity C-Reactive Protein and Its Relationship with Other Cardiovascular Risk Factors in the Middle-Aged Chinese Population. Int J Environ Res Public Health. 2016;13(9): 872
  • Ebong IA, Schreiner P, Lewis CE, Appiah D, Ghelani A, Wellons M. The Association between high-sensitivity C-reactive protein and hypertension in women of the CARDIA study. J North Am Menopause Soc. 2016;23(6):662–8.
  • Raeisi A, Ostovar A, Vahdat K, Rezaei P, Darabi H, Moshtaghi D, et al. Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women. Climacteric. 2017;20(1):44–8.
  • Koley S, Sur A. Association of Lipid Profile Parameters with High-Sensitive Câreactive Protein (hsCRP) in Patients with Dyslipidemia. Ann Med Health Sci Res. 2018;8(1):105–7.
  • Stepanikova I, Oates GR, Bateman LB. Does one size fit all?the role of body mass index and waist circumference in systemic inflammation in middle by race and gender. Ethnicity and Health. 2017; 22(2): 169-183.
  • Shahadan SZ, Daud A, Muhammad ML, Rasani AAM, Ibrahim M, Deraman S. Abdominal Obesity and High-sensitivity C-reactive Protein Level among Malay Obese Adults in Kuantan, Malaysia. Int Med J Malaysia. 2018;17(1):79–86.
  • Fan H, Li X, Zheng L, Chen X, Lan Q, Wu H, et al. Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese. Sci Rep. 2016;6:1–9.
  • Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease. Circ Res. 2016;118(11):1786–807.
  • Faam B, Zarkesh M, Daneshpour MS, Azizi F, Hedayati M. Association between abdominal obesity and hs-CRP, IL-6 and HCY in Tehranian adults : TLGS. Iranian Journal of Diabetes and Metabolism. 2014;13(2): 163-171.
  • Rokhmah FD, Handayani D, Al-Rasyid H. Korelasi Lingkar Pinggang dan Rasio Lingkar Pinggang-Panggul Terhadap Kadar Glukosa Plasma Menggunakan Tes Toleransi Glukosa Oral. J Gizi Klin Indones. 2017;12(1):28.
  • Eloi JC, Epifanio M, de Goncalves MM, Pellicioli A, Vieira PFG, Dias HB et al. Quantification of Abdominal fat in obese and healthy adolescent using 3 tesla magnetic resonance imaging and free software for image analysis. Plos One. 2017; 12(1): e0167625
  • Draganidis D, Jamurtas AZ, Stampoulis T, Laschou VC, Deli CK, Georgakouli K, et al. Disparate Habitual Physical Activity and Dietary Intake Profiles of Elderly Men with Low and Elevated Systemic Inflammation. Nutrients. 2018;10(5):1–16.
  • Cândida C, Martins DL, Emília F, Lima L De, Tony A. High-sensitivity c-reactive protein and total and saturated fat intake in adolescent students : a longitudinal study. BioRxiv. 2018: 1-27.

Downloads

Published

2021-07-31

How to Cite

1.
Fitranti DY, Syifarahmi B, Ardiaria M, Widyastuti N. Kadar High Sensitivity C-Reactive Protein Berkaitan dengan Lingkar Pinggang pada Lansia. IJHN [Internet]. 2021 Jul. 31 [cited 2024 Apr. 23];8(1):21-32. Available from: https://ijhn.ub.ac.id/index.php/ijhn/article/view/403

Issue

Vol. 8 No. 1 (2021)

Section

Articles

License

Creative Commons License
This work is licensed under a
Creative Commons Attribution-NonCommercial 4.0 International License

Most read articles by the same author(s)